Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[[(5-[[(3,4-Dimethoxyphenyl)sulfanyl]methyl]-1-(4-fluorophenyl)-1H-imidazol-2-yl)sulfanyl]methyl]-3,5-difluoro-N-[3-(trimethylazaniumyl)propyl]benzene-1-sulfonamide trifluoroacetate
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 PubChem ID
CID: 137641988
Canonical SMILES
COc1ccc(SCc2cnc(SCc3c(F)cc(S(=O)(=O)NCCC[N+](C)(C)C)cc3F)n2-c2ccc(F)cc2)cc1OC.O=C([O-])C(F)(F)F
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Compound Formula C33H36F6N4O6S3
Compound Structure
Protein Name
 Protein Info 
G-protein coupled bile acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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Steroid-like ligand receptor
Uniprot ID
Q8TDU6
Gene Name
GPBAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000126 NCI-H716
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 29550 nM
   TI
   LI
   LO
   TS