Brief Information of the Compound and Protein
Compound Name
5-[4-[[5-[(3,4-dimethoxyphenyl)sulfanylmethyl]-1-(4-fluorophenyl)imidazol-2-yl]sulfanylmethyl]-3,5-difluorophenyl]-2H-tetrazole
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PubChem ID
CID: 137651232
Canonical SMILES
COc1ccc(SCc2cnc(SCc3c(F)cc(cc3F)-c3nn[nH]n3)n2-c2ccc(F)cc2)cc1OC
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Compound Formula C26H21F3N6O2S2
Compound Structure
Protein Name
G-protein coupled bile acid receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Steroid-like ligand receptor
Uniprot ID
Q8TDU6
Gene Name
GPBAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000126 NCI-H716 Homo sapiens (Human)  1
1
EC50 = 42620 nM
   TI
   LI
   LO
   TS