Brief Information of the Compound and Protein
Compound Name
N-[[2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-3-(4-fluorophenyl)imidazol-4-yl]methyl]-N-(3,4-dimethoxyphenyl)formamide
    Show/Hide
PubChem ID
CID: 137634963
Canonical SMILES
COc1ccc(cc1OC)N(Cc1cnc(SCc2c(F)cccc2Cl)n1-c1ccc(F)cc1)C=O
    Show/Hide
Compound Formula C26H22ClF2N3O3S
Compound Structure
Protein Name
G-protein coupled bile acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Steroid-like ligand receptor
Uniprot ID
Q8TDU6
Gene Name
GPBAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000126 NCI-H716 Homo sapiens (Human)  1
1
EC50 = 21750 nM
   TI
   LI
   LO
   TS