Brief Information of the Compound and Protein
Compound Name
EED226
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PubChem ID
CID: 123132228
Canonical SMILES
CS(=O)(=O)c1ccc(cc1)-c1cnc(NCc2ccco2)n2cnnc12
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Compound Formula C17H15N5O3S
Compound Structure
Protein Name
Polycomb protein EED
Protein Classification
Unclassified protein
Uniprot ID
O75530
Gene Name
EED
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000175 G-401 Homo sapiens (Human)  1
1
IC50 = 220 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 12.2 nM
2 IC50 = 17.6 nM
3 IC50 = 20 nM
4 IC50 = 23.4 nM
5 IC50 = 45 nM
6 Kd = 82 nM