Brief Information of the Compound and Protein
Compound Name
(2S,4R)-4-(2-carboxyphenoxy)pyrrolidine-2-carboxylic acid;hydrochloride
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PubChem ID
CID: 137643975
Canonical SMILES
Cl.OC(=O)[C@@H]1C[C@H](CN1)Oc1ccccc1C(O)=O
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Compound Formula C12H14ClNO5
Compound Structure
Protein Name
Glutamate receptor ionotropic, kainate 1
Protein Classification
Ion channel
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Ligand-gated ion channel
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Ionotropic glutamate receptor
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Kainate receptor
Uniprot ID
P22756
Gene Name
GRIK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
IC50 = 5700 nM
   TI
   LI
   LO
   TS
CL000314 HEK293T/17 Homo sapiens (Human)  1
1
Ki = 2270 nM
   TI
   LI
   LO
   TS