Brief Information of the Compound and Protein
| Compound Name |
14C-5-hydroxy tryptamine creatinine disulfate
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
5-hydroxytryptamine receptor 5A
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Protein Classification |
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
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| Uniprot ID | Gene Name | HTR5A |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000006 | HEK293 | Homo sapiens (Human) | 3 |
| 1 |
IC50 = 180 nM
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TI
LI
LO
TS
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|---|---|---|---|
| 2 |
IC50 = 260 nM
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TI
LI
LO
TS
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| 3 |
Ki = 130 nM
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TI
LI
LO
TS
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Biochemical Assays
| 1 | IC50 = 79 nM | ||
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| 2 | IC50 = 160 nM | ||
| 3 | IC50 = 180 nM | ||
| 4 | IC50 = 184 nM | ||
| 5 | IC50 = 280 nM | ||
| 6 | Ki = 82 nM | ||
| 7 | Ki = 110 nM | ||
| 8 | Ki = 126 nM | ||
| 9 | Ki = 170 nM | ||
| 10 | Ki = 250 nM | ||