Brief Information of the Compound and Protein
Compound Name
2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-7-(4-chloro-3-methoxyphenyl)-1-(4-fluoro-3-methoxyphenyl)-4,5,6,7-tetrahydrobenzimidazole
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PubChem ID
CID: 118464758
Canonical SMILES
COc1cc(ccc1F)-n1c(SCc2c(F)cccc2Cl)nc2CCCC(c12)c1ccc(Cl)c(OC)c1
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Compound Formula C28H24Cl2F2N2O2S
Compound Structure
Protein Name
G-protein coupled bile acid receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Steroid-like ligand receptor
Uniprot ID
Q8TDU6
Gene Name
GPBAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000126 NCI-H716 Homo sapiens (Human)  1
1
EC50 = 30500 nM
   TI
   LI
   LO
   TS