Brief Information of the Compound and Protein
Compound Name
7-(1,3-benzodioxol-5-yl)-2-[(2-chloro-6-fluorophenyl)methylsulfanyl]-1-(4-fluorophenyl)-4,5,6,7-tetrahydrobenzimidazole
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PubChem ID
CID: 137656785
Canonical SMILES
Fc1ccc(cc1)-n1c(SCc2c(F)cccc2Cl)nc2CCCC(c12)c1ccc2OCOc2c1
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Compound Formula C27H21ClF2N2O2S
Compound Structure
Protein Name
G-protein coupled bile acid receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Steroid-like ligand receptor
Uniprot ID
Q8TDU6
Gene Name
GPBAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000126 NCI-H716 Homo sapiens (Human)  1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS