Brief Information of the Compound and Protein
Compound Name
2-[(2-bromo-6-fluorophenyl)methylsulfanyl]-7-(4-chloro-3-methoxyphenyl)-1-(4-fluorophenyl)-4,5,6,7-tetrahydrobenzimidazole
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PubChem ID
CID: 118464630
Canonical SMILES
COc1cc(ccc1Cl)C1CCCc2nc(SCc3c(F)cccc3Br)n(c12)-c1ccc(F)cc1
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Compound Formula C27H22BrClF2N2OS
Compound Structure
Protein Name
G-protein coupled bile acid receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Steroid-like ligand receptor
Uniprot ID
Q8TDU6
Gene Name
GPBAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000126 NCI-H716 Homo sapiens (Human)  1
1
EC50 > 50000 nM
   TI
   LI
   LO
   TS