Brief Information of the Compound and Protein
Compound Name
[(3aR,6aS)-2-(1-methylbenzimidazol-2-yl)-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
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PubChem ID
CID: 137655850
Canonical SMILES
Cc1ccc(c(c1)C(=O)N1C[C@H]2CN(C[C@H]2C1)c1nc2ccccc2n1C)-n1nccn1
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Compound Formula C24H25N7O
Compound Structure
Protein Name
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 1636 nM
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