Brief Information of the Compound and Protein
Compound Name
[(3aR,6aS)-2-[(5-chloro-1,3-benzoxazol-2-yl)methyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
    Show/Hide
PubChem ID
CID: 137637342
Canonical SMILES
Cc1ccc(c(c1)C(=O)N1C[C@@H]2CN(Cc3nc4cc(Cl)ccc4o3)C[C@@H]2C1)-n1nccn1
    Show/Hide
Compound Formula C24H23ClN6O2
Compound Structure
Protein Name
Orexin receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 1822 nM
   TI
   LI
   LO
   TS