Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-{[(3r,6r)-1-{[4-methoxy-2- (2h-1,2,3-triazol-2- yl)phenyl]carbonyl}-6- methylpiperidin-3-yl]oxy}-3- methylpyridine-4-carbonitrile
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 PubChem ID
CID: 74222241
Canonical SMILES
COc1ccc(C(=O)N2C[C@@H](CC[C@H]2C)Oc2nccc(C#N)c2C)c(c1)-n1nccn1
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Compound Formula C23H24N6O3
Compound Structure
Protein Name
 Protein Info 
Orexin receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
2
Ki = 1.3 nM
   TI
   LI
   LO
   TS