Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9546152, example 89
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 PubChem ID
CID: 74221990
Canonical SMILES
C[C@@H]1CC[C@H](CN1C(=O)c1ccc(Br)nc1-n1nccn1)Oc1nccc(C#N)c1C
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Compound Formula C21H20BrN7O2
Compound Structure
Protein Name
 Protein Info 
Orexin receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 29 nM
   TI
   LI
   LO
   TS
2
Ki = 5.1 nM
   TI
   LI
   LO
   TS