Brief Information of the Compound and Protein
Compound Name
RICOLINOSTAT
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PubChem ID
CID: 53340666
SID: 125005606
Canonical SMILES
ONC(=O)CCCCCCNC(=O)c1cnc(nc1)N(c1ccccc1)c1ccccc1
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Compound Formula C24H27N5O3
Compound Structure
Protein Name
Histone deacetylase 1
Protein Classification
Epigenetic regulator
>
Eraser
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Histone deacetylase
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HDAC class I
Uniprot ID
Q13547
Gene Name
HDAC1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  3
1
IC50 = 58 nM
   TI
   LI
   LO
   TS
2
IC50 = 74 nM
   TI
   LI
   LO
   TS
3
IC50 = 100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 16 nM
2 IC50 = 19 nM
3 IC50 = 38 nM
4 IC50 = 53 nM
5 IC50 = 58 nM
6 IC50 = 130 nM
7 IC50 = 187.9 nM
8 IC50 = 190 nM
9 IC50 = 390 nM
10 Ki = 74 nM