Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9464084, 154
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 PubChem ID
CID: 90408953
Canonical SMILES
Cc1c(C(=O)N2Cc3nnn(-c4cc[nH]n4)c3CC2C)cccc1C(F)(F)F
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Compound Formula C18H17F3N6O
Compound Structure
Protein Name
 Protein Info 
P2X purinoceptor 7
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
P2X receptor
Uniprot ID
Q64663
Gene Name
P2RX7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 10.2 nM
   TI
   LI
   LO
   TS