Brief Information of the Compound and Protein
Compound Name
US9427442, 9
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PubChem ID
CID: 90083107
Canonical SMILES
Cc1cccc2c1NC(=O)[C@@H](NC(=O)[C@H](CCC(F)(F)F)[C@H](CC1CC(F)(F)C1)C(N)=O)N=C2c1cccc(F)c1
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Compound Formula C28H28F6N4O3
Compound Structure
Protein Name
Neurogenic locus notch homolog protein 1
Protein Classification
Membrane receptor
Uniprot ID
P46531
Gene Name
NOTCH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
IC50 = 3.5 nM
   TI
   LI
   LO
   TS