Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9427442, 3
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 PubChem ID
CID: 73442312
Canonical SMILES
NC(=O)[C@H]([C@@H](CCC(F)(F)F)C(=O)N[C@H]1N=C(c2cccc(F)c2)c2cccc(OC3CC3)c2NC1=O)C1CCC(F)(F)CC1
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Compound Formula C31H32F6N4O4
Compound Structure
Protein Name
 Protein Info 
Neurogenic locus notch homolog protein 1
Protein Classification
Membrane receptor
Uniprot ID
P46531
Gene Name
NOTCH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 4.2 nM
   TI
   LI
   LO
   TS