Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(E,3R,5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-N,3,5-trihydroxyhept-6-enamide
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 PubChem ID
CID: 71655139
Canonical SMILES
CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(=O)NO)N(C)S(C)(=O)=O
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Compound Formula C22H29FN4O6S
Compound Structure
Protein Name
 Protein Info 
3-hydroxy-3-methylglutaryl-coenzyme A reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P04035
Gene Name
HMGCR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 43.7 nM
   TI
   LI
   LO
   TS
2
IC50 = 14900 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 43.7 nM