Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid
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 PubChem ID
CID: 60823
SID: 14910832
Canonical SMILES
CC(C)c1c(C(=O)Nc2ccccc2)c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC(O)=O)-c1ccccc1
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Compound Formula C33H35FN2O5
Compound Structure
Protein Name
 Protein Info 
3-hydroxy-3-methylglutaryl-coenzyme A reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P04035
Gene Name
HMGCR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 11.6 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.227 nM
2 IC50 = 6 nM
3 IC50 = 12.9 nM
4 Ki = 6.2 nM