Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9346798, 212
    Show/Hide
 PubChem ID
CID: 71711363
Canonical SMILES
FC(F)(F)c1ccc(N2CCOc3cc(c(Cl)cc23)S(=O)(=O)Nc2nccs2)c(c1)C#N
    Show/Hide
Compound Formula C19H12ClF3N4O3S2
Compound Structure
Protein Name
 Protein Info 
Sodium channel protein type 9 subunit alpha
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Voltage-gated sodium channel
Uniprot ID
Q15858
Gene Name
SCN9A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  4
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
2
IC50 = 21.3 nM
   TI
   LI
   LO
   TS
3
IC50 = 373 nM
   TI
   LI
   LO
   TS
4
IC50 = 390 nM
   TI
   LI
   LO
   TS