Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9340500, I-121
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 PubChem ID
CID: 71466193
SID: 163428842
Canonical SMILES
CNCC(F)(F)Cn1c(C)c(cc1C(C)(C)C)C(=O)Nc1cccc(c1)C(F)(F)F
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Compound Formula C21H26F5N3O
Compound Structure
Protein Name
 Protein Info 
Transient receptor potential cation channel subfamily V member 4
Protein Classification
Ion channel
>
Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
Q9HBA0
Gene Name
TRPV4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001031 hTRPV4/CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 1400 nM
   TI
   LI
   LO
   TS
2
Ki = 450 nM
   TI
   LI
   LO
   TS