Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9340500, I-081
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 PubChem ID
CID: 71465982
SID: 163428518
Canonical SMILES
Cc1c(NC(=O)Nc2cccc(c2)C(F)(F)F)cc(-c2ccccc2)n1CCCN1CCOCC1
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Compound Formula C26H29F3N4O2
Compound Structure
Protein Name
 Protein Info 
Transient receptor potential cation channel subfamily V member 4
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
Q9HBA0
Gene Name
TRPV4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001031 hTRPV4/CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 3900 nM
   TI
   LI
   LO
   TS
2
Ki = 1611 nM
   TI
   LI
   LO
   TS