Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9340500, I-083
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 PubChem ID
CID: 71465984
SID: 163428520
Canonical SMILES
Cc1c(cc(-c2ccccc2)n1CCN1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F
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Compound Formula C25H26F3N3O2
Compound Structure
Protein Name
 Protein Info 
Transient receptor potential cation channel subfamily V member 4
Protein Classification
Ion channel
>
Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
Q9HBA0
Gene Name
TRPV4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001031 hTRPV4/CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 400 nM
   TI
   LI
   LO
   TS
2
Ki = 443 nM
   TI
   LI
   LO
   TS