Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9315498, 28
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 PubChem ID
CID: 53493360
SID: 126721011
Canonical SMILES
CC1(C)OC(=O)N(c2ccc(cn2)C#Cc2ccccc2)C1(C)C
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Compound Formula C20H20N2O2
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 48 nM
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