Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9278960, 4-96
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 PubChem ID
CID: 89554790
Canonical SMILES
Cn1cc(cn1)-c1cc(nc2cc(CN3C[C@@H](OCC3(C)C)C(F)(F)F)ccc12)C(N)=O
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Compound Formula C22H24F3N5O2
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000389 CHO-DXB11
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 8 nM
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