Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9278960, 4-90
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 PubChem ID
CID: 89554961
Canonical SMILES
C[C@@H]1CO[C@H](CN1Cc1ccc2c(cc(nc2c1)C(N)=O)-c1cnn(C)c1)C(F)(F)F
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Compound Formula C21H22F3N5O2
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000389 CHO-DXB11
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 8 nM
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