Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9278960, 1-24
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 PubChem ID
CID: 71566522
SID: 163592898
Canonical SMILES
NC(=O)c1cc(-c2ccc(F)cc2)c2ccccc2n1
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Compound Formula C16H11FN2O
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000389 CHO-DXB11
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 169 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 149 nM