Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9090625, 4
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 PubChem ID
CID: 24880914
SID: 50136582
Canonical SMILES
CCc1cnn(c1-c1cc2cnccc2s1)-c1cccc(C)n1
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Compound Formula C18H16N4S
Compound Structure
Protein Name
 Protein Info 
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 21.5 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 4.33 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.3 nM
2 IC50 = 4.33 nM