Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9255103, 28
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 PubChem ID
CID: 67968082
Canonical SMILES
Fc1ccc(cc1C#N)C(=O)N1CCn2nc(COc3ccccc3)cc2C1
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Compound Formula C21H17FN4O2
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 1660 nM
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