Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9242977, 48
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 PubChem ID
CID: 89880990
Canonical SMILES
CCNc1ncc(s1)-c1ccc(Oc2ncc(NC(=O)Nc3cc(cnc3Oc3ccccc3)C(F)(F)F)cn2)cc1
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Compound Formula C28H22F3N7O3S
Compound Structure
Protein Name
 Protein Info 
High affinity nerve growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 120 nM