Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US8614253, 26-12
    Show/Hide
 PubChem ID
CID: 136076125
Canonical SMILES
Oc1c(F)cc(cc1C=O)-c1cccc2ncccc12
    Show/Hide
Compound Formula C16H10FNO2
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase/endoribonuclease IRE1
Protein Classification
Enzyme
Uniprot ID
O75460
Gene Name
ERN1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 80000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 305 nM