Brief Information of the Compound and Protein
Compound Name
US9212171, 5
    Show/Hide
PubChem ID
CID: 70937836
SID: 163426765
Canonical SMILES
CN1C(=O)C(CC1(C)C)(C(=O)OCc1ccccc1)c1ncc(cn1)C#Cc1ccccc1
    Show/Hide
Compound Formula C27H25N3O3
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 528 nM
   TI
   LI
   LO
   TS