Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(3S)-1-[(2-amino-3H-benzimidazol-5-yl)methyl]-2-oxopyrrolidin-3-yl]-7-methoxynaphthalene-2-sulfonamide
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 PubChem ID
CID: 134146016
Canonical SMILES
COc1ccc2ccc(S(=O)(=O)N[C@H]3CCN(Cc4ccc5nc(N)[nH]c5c4)C3=O)cc2c1
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Compound Formula C23H23N5O4S
Compound Structure
Protein Name
 Protein Info 
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 115.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3040 nM
2 IC50 = 3190 nM
3 IC50 = 3340 nM
4 IC50 = 3550 nM
5 IC50 = 3740 nM
6 IC50 = 3750 nM
7 IC50 = 3950 nM
8 IC50 = 4280 nM
9 IC50 = 5070 nM
10 IC50 = 7020 nM
11 Kd = 2387.5 nM