Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[2-[(5-chloropyridin-2-yl)amino]-2-oxoethyl]-N-[4-(2-oxopyrazin-1-yl)phenyl]benzimidazole-2-carboxamide
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 PubChem ID
CID: 67012933
Canonical SMILES
O=C(Cn1c(C(=O)Nc2ccc(-n3ccncc3=O)cc2)nc2ccccc21)Nc1ccc(Cl)cn1
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Compound Formula C25H18ClN7O3
Compound Structure
Protein Name
 Protein Info 
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 152 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 8.98 nM
2 IC50 = 10.6 nM
3 IC50 = 11.6 nM
4 IC50 = 11.9 nM
5 IC50 = 12 nM
6 IC50 = 12.7 nM
7 IC50 = 13.3 nM
8 IC50 = 13.4 nM
9 IC50 = 13.9 nM
10 IC50 = 14.1 nM
11 IC50 = 16.7 nM
12 IC50 = 17.2 nM
13 Kd = 77.49 nM