Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]methyl]-5-(hydroxymethyl)-N-[4-(3-oxomorpholin-4-yl)phenyl]pyrazole-3-carboxamide
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 PubChem ID
CID: 9958105
SID: 14933818
Canonical SMILES
O=C(Nc1ccc(N2CCOCC2=O)cc1)c1cc(CO)n(Cc2cc(-c3ccc(Cl)s3)on2)n1
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Compound Formula C23H20ClN5O5S
Compound Structure
Protein Name
 Protein Info 
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 33.43 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.13 nM
2 IC50 = 1.22 nM
3 IC50 = 1.24 nM
4 IC50 = 1.39 nM
5 IC50 = 1.4 nM
6 IC50 = 1.58 nM
7 IC50 = 1.59 nM
8 IC50 = 1.61 nM
9 IC50 = 1.64 nM
10 IC50 = 1.8 nM
11 IC50 = 1.83 nM
12 Kd = 37.4 nM