Brief Information of the Compound and Protein
| Compound Name |
5-chloro-N-[2-[[4-(2-oxopyrazin-1-yl)phenyl]sulfamoyl]ethyl]thiophene-2-carboxamide
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
Coagulation factor X
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Protein Classification |
Enzyme
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Protease
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Serine protease
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Serine protease PA clan
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Serine protease S1A subfamily
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| Uniprot ID | Gene Name | F10 |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000013 | Sf9 | Spodoptera frugiperda (Fall armyworm) | 1 |
| 1 |
Kd = 55.17 nM
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TI
LI
LO
TS
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|---|---|---|---|
Biochemical Assays
| 1 | IC50 = 26.7 nM | ||
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| 2 | IC50 = 29.7 nM | ||
| 3 | IC50 = 29.9 nM | ||
| 4 | IC50 = 30 nM | ||
| 5 | IC50 = 31.2 nM | ||
| 6 | IC50 = 32.2 nM | ||
| 7 | IC50 = 32.9 nM | ||
| 8 | IC50 = 34.2 nM | ||
| 9 | IC50 = 38.5 nM | ||
| 10 | IC50 = 47.5 nM | ||
| 11 | Kd = 37.93 nM | ||