Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]methyl]-2-[(1-cyclopropylpiperidin-4-yl)carbamoyl]benzimidazole-5-carboxylic acid
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 PubChem ID
CID: 53316387
Canonical SMILES
O=C(O)c1ccc2c(c1)nc(C(=O)NC1CCN(C3CC3)CC1)n2Cc1cc(-c2ccc(Cl)s2)on1
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Compound Formula C25H24ClN5O4S
Compound Structure
Protein Name
 Protein Info 
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 27.03 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 18.1 nM
2 IC50 = 18.3 nM
3 IC50 = 19.2 nM
4 IC50 = 19.7 nM
5 IC50 = 19.8 nM
6 IC50 = 20.4 nM
7 IC50 = 21 nM
8 IC50 = 21.4 nM
9 IC50 = 21.6 nM
10 IC50 = 23.8 nM
11 IC50 = 24.8 nM
12 Kd = 34.21 nM