Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-chloro-N-[3-oxo-3-[4-(3-oxomorpholin-4-yl)-3-(trifluoromethyl)anilino]propyl]thiophene-2-carboxamide
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 PubChem ID
CID: 134132943
Canonical SMILES
O=C(CCNC(=O)c1ccc(Cl)s1)Nc1ccc(N2CCOCC2=O)c(C(F)(F)F)c1
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Compound Formula C19H17ClF3N3O4S
Compound Structure
Protein Name
 Protein Info 
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 42.4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.9 nM
2 IC50 = 1.91 nM
3 IC50 = 2.01 nM
4 IC50 = 2.55 nM
5 IC50 = 2.62 nM
6 IC50 = 3.11 nM
7 IC50 = 3.38 nM
8 IC50 = 3.4 nM
9 IC50 = 3.63 nM
10 IC50 = 3.71 nM
11 IC50 = 3.93 nM
12 IC50 = 4.57 nM
13 Kd = 13.07 nM