Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[[(5-chlorothiophene-2-carbonyl)amino]methyl]-N-[2-fluoro-4-(2-oxopyridin-1-yl)phenyl]-1,2,4-oxadiazole-5-carboxamide
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 PubChem ID
CID: 24776448
SID: 49701108
Canonical SMILES
O=C(Nc1ccc(-n2ccccc2=O)cc1F)c1nc(CNC(=O)c2ccc(Cl)s2)no1
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Compound Formula C20H13ClFN5O4S
Compound Structure
Protein Name
 Protein Info 
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 5.003 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.64 nM
2 IC50 = 0.667 nM
3 IC50 = 0.674 nM
4 IC50 = 0.708 nM
5 IC50 = 0.723 nM
6 IC50 = 0.757 nM
7 IC50 = 0.774 nM
8 IC50 = 0.796 nM
9 IC50 = 0.816 nM
10 IC50 = 0.819 nM
11 IC50 = 0.856 nM
12 IC50 = 0.891 nM
13 Kd = 1.88 nM