Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-chloro-N-[1-[2-[2-fluoro-4-(2-oxopyridin-1-yl)anilino]-2-oxoethyl]-4-methoxypyrrolidin-3-yl]thiophene-2-carboxamide
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 PubChem ID
CID: 73160226
Canonical SMILES
COC1CN(CC(=O)Nc2ccc(-n3ccccc3=O)cc2F)CC1NC(=O)c1ccc(Cl)s1
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Compound Formula C23H22ClFN4O4S
Compound Structure
Protein Name
 Protein Info 
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 5.397 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.976 nM
2 IC50 = 1.03 nM
3 IC50 = 1.04 nM
4 IC50 = 1.06 nM
5 IC50 = 1.1 nM
6 IC50 = 1.14 nM
7 IC50 = 1.15 nM
8 IC50 = 1.16 nM
9 IC50 = 1.21 nM