Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(3S)-1-(4,7-diazabicyclo[4.3.0]nona-2,4,8,10-tetraen-8-ylmethyl)-2-oxo-pyrrolidin-3-yl]-7-thia-2-azabicyclo[4.3.0]nona-2,4,8,10-tetraene-8-sulfonamide
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 PubChem ID
CID: 445481
SID: 14807378
Canonical SMILES
O=C1[C@H](CCN1Cc1cc2ccncc2[nH]1)NS(=O)(=O)c1cc2ncccc2s1
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Compound Formula C19H17N5O3S2
Compound Structure
Protein Name
 Protein Info 
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 83.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 19.3 nM
2 IC50 = 20.3 nM
3 IC50 = 20.5 nM
4 IC50 = 21.8 nM
5 IC50 = 22.9 nM
6 IC50 = 25.5 nM
7 IC50 = 25.9 nM
8 IC50 = 27.4 nM
9 IC50 = 27.6 nM
10 IC50 = 27.8 nM
11 IC50 = 31.2 nM
12 Kd = 4.938 nM