Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-Chloro-N-{[(5S)-3-(3-fluoro-4-thiomorpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}thiophene-2-carboxamide
    Show/Hide
 PubChem ID
CID: 10161422
SID: 15154581
Canonical SMILES
Fc1cc(ccc1N1CCSCC1)N1C[C@H](CNC(=O)c2ccc(Cl)s2)OC1=O
    Show/Hide
Compound Formula C19H19ClFN3O3S2
Compound Structure
Protein Name
 Protein Info 
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 179 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 12.9 nM
2 IC50 = 13.5 nM
3 IC50 = 13.7 nM
4 IC50 = 14.7 nM
5 IC50 = 15 nM
6 IC50 = 15.2 nM
7 IC50 = 16.1 nM
8 IC50 = 17.2 nM
9 IC50 = 17.4 nM
10 IC50 = 17.7 nM
11 IC50 = 17.9 nM
12 IC50 = 90 nM
13 Kd = 33.12 nM