Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[2-(4-bromoanilino)-2-oxoethyl]-N-(1-propan-2-ylpiperidin-4-yl)indole-2-carboxamide
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 PubChem ID
CID: 102481209
Canonical SMILES
CC(C)N1CCC(CC1)NC(=O)c1cc2ccccc2n1CC(=O)Nc1ccc(Br)cc1
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Compound Formula C25H29BrN4O2
Compound Structure
Protein Name
 Protein Info 
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 44.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.71 nM
2 IC50 = 1.8 nM
3 IC50 = 2.03 nM
4 IC50 = 2.11 nM
5 IC50 = 2.17 nM
6 IC50 = 2.39 nM
7 IC50 = 2.4 nM
8 IC50 = 2.65 nM
9 IC50 = 2.66 nM
10 IC50 = 2.81 nM
11 IC50 = 2.87 nM
12 IC50 = 2.96 nM
13 Kd = 2.014 nM
14 Ki = 3 nM