Brief Information of the Compound and Protein
Compound Name
5-Chloro-N-({(5R)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-sulfonamide
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PubChem ID
CID: 11619782
SID: 16722693
Canonical SMILES
Clc1ccc(s1)S(=O)(=O)NC[C@H]1CN(C(=O)O1)c1ccc(cc1)N1CCOCC1=O
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Compound Formula C18H18ClN3O6S2
Compound Structure
Protein Name
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 177.95 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 397 nM
2 IC50 = 411 nM
3 IC50 = 415 nM
4 IC50 = 425 nM
5 IC50 = 440 nM
6 IC50 = 449 nM
7 IC50 = 471 nM
8 IC50 = 483 nM
9 IC50 = 502 nM
10 IC50 = 508 nM
11 IC50 = 514 nM
12 IC50 = 517 nM
13 IC50 = 1200 nM