Brief Information of the Compound and Protein
Compound Name |
2-Chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)-1,3-thiazole-5-carboxamide
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PubChem ID | |||||
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Compound Structure |
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Protein Name |
Coagulation factor X
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Protein Classification |
Enzyme
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Protease
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Serine protease
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Serine protease PA clan
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Serine protease S1A subfamily
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Uniprot ID | Gene Name | F10 |
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID | Cell Line Name | Cell Line Organism | |
CL000013 | Sf9 | Spodoptera frugiperda (Fall armyworm) | 1 |
1 |
Kd = 191.5 nM
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TI
LI
LO
TS
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Biochemical Assays
1 | IC50 = 105 nM | ||
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2 | IC50 = 140 nM | ||
3 | IC50 = 152 nM | ||
4 | IC50 = 155 nM | ||
5 | IC50 = 160 nM | ||
6 | IC50 = 167 nM | ||
7 | IC50 = 173 nM | ||
8 | IC50 = 175 nM | ||
9 | IC50 = 186 nM | ||
10 | IC50 = 189 nM | ||
11 | IC50 = 290 nM |