Brief Information of the Compound and Protein
Compound Name
2-Chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)-1,3-thiazole-5-carboxamide
    Show/Hide
PubChem ID
CID: 11618984
SID: 16721908
Canonical SMILES
Clc1ncc(s1)C(=O)NC[C@H]1CN(C(=O)O1)c1ccc(cc1)N1CCOCC1=O
    Show/Hide
Compound Formula C18H17ClN4O5S
Compound Structure
Protein Name
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 191.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 105 nM
2 IC50 = 140 nM
3 IC50 = 152 nM
4 IC50 = 155 nM
5 IC50 = 160 nM
6 IC50 = 167 nM
7 IC50 = 173 nM
8 IC50 = 175 nM
9 IC50 = 186 nM
10 IC50 = 189 nM
11 IC50 = 290 nM