Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2R,3R)-2-(3-Carbamimidoyl-benzyl)-3-[4-(1-oxy-pyridin-4-yl)-benzoylamino]-butyric acid methyl ester
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 PubChem ID
CID: 5496659
SID: 123055317
Canonical SMILES
COC(=O)[C@H](Cc1cccc(c1)C(N)=N)[C@@H](C)NC(=O)c1ccc(cc1)-c1cc[n+]([O-])cc1
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Compound Formula C25H26N4O4
Compound Structure
Protein Name
 Protein Info 
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 16.84 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.586 nM
2 IC50 = 0.623 nM
3 IC50 = 0.682 nM
4 IC50 = 0.702 nM
5 IC50 = 0.734 nM
6 IC50 = 0.747 nM
7 IC50 = 0.784 nM
8 IC50 = 0.823 nM
9 IC50 = 0.851 nM
10 IC50 = 0.865 nM
11 IC50 = 0.929 nM
12 IC50 = 0.933 nM
13 Kd = 89.31 nM
14 Ki = 0.4 nM
15 Ki = 0.5 nM