Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-Chloro-N-{[(5S)-3-(3-fluoro-4-pyrrolidin-1-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}thiophene-2-carboxamide
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 PubChem ID
CID: 11553603
SID: 16655842
Canonical SMILES
Fc1cc(ccc1N1CCCC1)N1C[C@H](CNC(=O)c2ccc(Cl)s2)OC1=O
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Compound Formula C19H19ClFN3O3S
Compound Structure
Protein Name
 Protein Info 
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 309 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.11 nM
2 IC50 = 1.58 nM
3 IC50 = 1.62 nM
4 IC50 = 1.66 nM
5 IC50 = 1.72 nM
6 IC50 = 2.01 nM
7 IC50 = 2.03 nM
8 IC50 = 2.06 nM
9 IC50 = 2.12 nM
10 IC50 = 2.18 nM
11 IC50 = 2.28 nM
12 IC50 = 2.32 nM
13 IC50 = 40 nM
14 Kd = 7.76 nM