Brief Information of the Compound and Protein
Compound Name
 Compound Info 
BAY 59-7939 Analog 14
    Show/Hide
 PubChem ID
CID: 11583256
SID: 16685695
Canonical SMILES
Nc1cc(ccc1N1CCOCC1=O)N1C[C@H](CNC(=O)c2ccc(Cl)s2)OC1=O
    Show/Hide
Compound Formula C19H19ClN4O5S
Compound Structure
Protein Name
 Protein Info 
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 7.16 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.658 nM
2 IC50 = 0.676 nM
3 IC50 = 0.737 nM
4 IC50 = 0.742 nM
5 IC50 = 0.765 nM
6 IC50 = 0.787 nM
7 IC50 = 0.803 nM
8 IC50 = 0.808 nM
9 IC50 = 0.824 nM
10 IC50 = 0.839 nM
11 IC50 = 0.854 nM
12 IC50 = 0.863 nM
13 IC50 = 2.5 nM
14 Kd = 2.3 nM