Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-Bromo-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-2-furamide
    Show/Hide
 PubChem ID
CID: 10161902
SID: 15155066
Canonical SMILES
Brc1ccc(o1)C(=O)NC[C@H]1CN(C(=O)O1)c1ccc(cc1)N1CCOCC1=O
    Show/Hide
Compound Formula C19H18BrN3O6
Compound Structure
Protein Name
 Protein Info 
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 13.4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.88 nM
2 IC50 = 3.61 nM
3 IC50 = 3.67 nM
4 IC50 = 3.89 nM
5 IC50 = 3.96 nM
6 IC50 = 4.08 nM
7 IC50 = 4.18 nM
8 IC50 = 4.21 nM
9 IC50 = 4.29 nM
10 IC50 = 4.52 nM
11 IC50 = 4.76 nM
12 IC50 = 4.99 nM
13 IC50 = 26 nM
14 Kd = 18.4 nM