Brief Information of the Compound and Protein
Compound Name
4-chloro-N-{[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl}benzamide
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PubChem ID
CID: 9932394
SID: 15225564
Canonical SMILES
Clc1ccc(cc1)C(=O)NC[C@H]1CN(C(=O)O1)c1ccc(cc1)N1CCOCC1=O
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Compound Formula C21H20ClN3O5
Compound Structure
Protein Name
Coagulation factor X
Protein Classification
Enzyme
>
Protease
>
Serine protease
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Serine protease PA clan
>
Serine protease S1A subfamily
Uniprot ID
P00742
Gene Name
F10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
Kd = 15 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.58 nM
2 IC50 = 4.07 nM
3 IC50 = 4.27 nM
4 IC50 = 4.38 nM
5 IC50 = 4.43 nM
6 IC50 = 4.55 nM
7 IC50 = 4.59 nM
8 IC50 = 4.6 nM
9 IC50 = 4.77 nM
10 IC50 = 4.92 nM
11 IC50 = 5.47 nM
12 IC50 = 20 nM
13 Kd = 20.9 nM